paroxysmal nocturnal haemoglobinuria
paroxysmal nocturnal hemoglobinuria

Haemaglobinuria in the morning is suggestive of paroxysmal nocturnal haemoglobinuria.

A rare condition, paroxysmal nocturnal haemoglobinuria, results in red cells which lack CD59.

All of these, except paroxysmal nocturnal hemoglobinuria, are hereditary genetic disorders.

Paroxysmal nocturnal hemoglobinuria.

Paroxysmal nocturnal hemoglobinuria (rare acquired clonal disorder of red blood cell surface proteins)

Paroxysmal nocturnal hemoglobinuria; the mechanism of hemolysis and its relation to the coagulation mechanism.

Hemosiderin in the kidneys have been associated with marked hemolysis and a rare blood disorder called paroxysmal nocturnal hemoglobinuria.

An uncommon blood disease called paroxysmal nocturnal hemoglobinuria can cause blood clots in the liver, the spleen or beneath the skin.

Defects of 'GPI anchors' occur in the rare disease paroxysmal nocturnal hemoglobinuria.

In some cases, aplastic anemia is associated with another blood disorder called paroxysmal nocturnal hemoglobinuria (PNH).

Castle and his team later characterized the red blood cell defects that are responsible for paroxysmal nocturnal hemoglobinuria and hereditary spherocytosis.

The Ham test is a test used in the diagnosis of paroxysmal nocturnal hemoglobinuria (PNH).

Acquired thrombophilia (antiphospholipid syndrome, nephrotic syndrome, paroxysmal nocturnal hemoglobinuria)

In general, low platelet counts increase bleeding risks; however there are exceptions (such as immune-mediated heparin-induced thrombocytopenia or paroxysmal nocturnal hemoglobinuria).

In 1931, it described Paroxysmal nocturnal hemoglobinuria in depth, and also a rare form of this disease Strübing-Marchiafava-Micheli Syndrome.

The Dutch physician Enneking coined the term "paroxysmal nocturnal hemoglobinuria" (or haemoglobinuria paroxysmalis nocturna in Latin) in 1928.

To formally diagnose agranulocytosis, other pathologies with a similar presentation must be excluded, such as aplastic anemia, paroxysmal nocturnal hemoglobinuria, myelodysplasia and leukemias.

Paroxysmal nocturnal hemoglobinuria is caused by complement breakdown of RBCs due to an inability to make GPI.

Mutations affecting GPI that reduce expression of CD59 and decay-accelerating factor on red blood cells result in paroxysmal nocturnal hemoglobinuria.

In those with paroxysmal nocturnal hemoglobinuria despite best historical care (e.g., anticoagulation therapy, transfusions), 35% of patients with PNH die within 5 years of diagnosis.

Most notably, deficiency of the MAC inhibitor CD59 results in an overactivity of complement and Paroxysmal nocturnal hemoglobinuria.

Disorders of the proteins in these membranes are associated with many disorders, such as hereditary spherocytosis, hereditary elliptocytosis, hereditary stomatocytosis, and paroxysmal nocturnal hemoglobinuria.

Fluorescein-labeled proaerolysin (FLAER) is a flow cytometric assay used to diagnose paroxysmal nocturnal hemoglobinuria (PNH).

PNH Marchiafava-Micheli syndrome None Paroxysmal nocturnal hemoglobinuria (PNH) is a rare disorder in which red blood cells break apart prematurely.

Alexion Pharmaceuticals is the original developer and distributor of Soliris, a drug used in treating the rare disorders Hemolytic-uremic syndrome and Paroxysmal nocturnal hemoglobinuria (PNH).

In the last quarter R&D spending was higher due to expansion of development programs while net sales of Soliris increased 45% to $227.6 million on account of new international patients with paroxysmal nocturnal hemoglobinuria.

Genetic defects in GPI-anchor attachment that cause a reduction or loss of both CD59 and CD55 on erythrocytes produce the symptoms of the disease paroxysmal nocturnal hemoglobinuria (PNH).