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The average diameter of developing and atretic follicles within groups was similar (data not shown).
Mean diameters of developing and atretic follicles per individual animal were the basis for comparison between groups.
The number of developing antral follicles per female exceeded those that were atretic in all but three females in the study.
One of these females had 3 atretic follicles and the other had 6 developing follicles.
The malformations can be atretic or fibrocystic.
Follicles that have fewer FSH-receptors will not be able to develop further; they will show retardation of their growth rate and become atretic.
In some cases the end of the smaller left aortic arch closes (left atretic arch) and the vascular tissue becomes a fibrous cord.
In atretic follicles BMP-3b mRNA expression was undetectable (Fig.
Unlike healthy follicles, BMP-4 mRNA was very low or undetectable in atretic follicles.
The proportion of total antral follicles per female that was atretic was used as an index of atresia (atresia, hereinafter).
The corpus albicans is also known as atretic corpus luteum, corpus candicans, or simply as albicans.
Non-perfused elements of other types of vascular rings (e.g. left arch with atretic (closed) end) or the ligamentum arteriosum might be difficult to visualize by echocardiography.
High levels of BMP-6 mRNA were present in oocytes of all Graafian follicles, both healthy and atretic (Fig.
Finally the highest levels of BMP-2 mRNA in the ovary were seen in the GC of atretic follicles (Fig.
Cells in atretic follicles (GC and oocyte) continued to show high expression of BMPR-IB mRNA (Fig.
Atretic follicles were identified by the presence of 5 or more pyknotic nuclei in granulosa cells, leukocytes in the antrum, and loosening or degeneration of the mural layer of granulosa cells.
In babies with HLHS, the aorta and left ventricle are underdeveloped before birth, and the aortic and mitral valves are either too small to allow sufficient blood flow or are atretic (closed) altogether.
This, together with the failure to detect BMP-4 and 7 in the theca of atretic follicles, supports the idea that the cellular sites and coordinate expression of these BMP genes may have important regulatory roles in maintaining folliculogenesis.