Howell-Jolly body

On a blood smear, Howell-Jolly bodies may be seen within red blood cells.

A blood film may show features of hyposplenism (target cells and Howell-Jolly bodies).

In newly formed red blood cells in humans, these are known as Howell-Jolly bodies.

Howell-Jolly bodies are also seen in:

Splenectomy patients typically have Howell-Jolly bodies and less commonly Heinz bodies in their blood smears.

Ten percent of patients with Coeliac disease also present with splenic atrophy with subsequent Howell-Jolly bodies.

Howell-Jolly bodies are histopathological findings of basophilic nuclear remnants (clusters of DNA) in circulating erythrocytes.

Howell-Jolly bodies: small, round fragments of the nucleus resulting from karyorrhexis or nuclear disintegration of the late reticulocyte and stain reddish-blue with Wright stain.

Micronuclei are also referred to Howell-Jolly bodies; discovered by hematologists William Henry Howell and Justin Marie Jolly in erythrocytes.

Bass' Hive series of stories are replete with obvious and not-so-obvious references to nomenclature commonly used in pathology, including eponymic puns (note a male character's observation of a female character's attractive "Howell-Jolly body").