At the very least it would mean the end of your business relationship.

For some this will mean the end of the course.

One word from you will mean the end of your political career.

But that would mean the end, because my life is to work.

To have had two as I did meant the end of me.

"Then what is the whole meaning of the past or even the present, if the future only means the end?"

Plans that could very well mean the end of the human race.

If he does not, it could mean the end of his career.

If they do, it would probably mean the end of the 10-year-old company.

It might mean the end of this long war with them after all.